Epigenetics and ethics

April 12, 2013

It is a well established truth that not all of our genes are switched on in all of our cells all of the time. A fundamental role in the control of gene expression is played by transcription factors encoded within the DNA itself. In addition to this, however, there is now increasing recognition of the importance of an additional layer of genetic modification over and above the sequence of A,C,G&T letters in genome.

The epigenetics teaching resources have been developed by Lyndsey Wright as part of the public engagement with science component of her PhD (funded by the BBSRC)

The epigenetics teaching resources have been developed by Lyndsey Wright during the public engagement with science component of her PhD (funded by the BBSRC)

This “epigenetic” regulation can be influenced by environmental factors and hence questions about the ethical significance of epigenetics are emerging. Two different resources for looking at these bioethical dimension of epigenetics have recently been launched.

Firstly, PhD student Lyndsey Wright has taken the lead in the developed a series of resources on epigenetics and ethics which can be used with A-level students and undergraduates.

Four case studies are included on:

The resource, which is part of the wider Virtual Genetics Education Centre, includes teachers’ notes, student worksheets and PowerPoint presentations as well as links to further reading.

The second new resource is a video on the science and ethics of epigenetics.

The video includes consideration of Jesus and his (fictional) twin Joshua

The video includes consideration of Jesus and his (fictional) twin Joshua

This film was made by second year undergraduates at Leicester as an assessed piece of work. The video includes interviews with a number of scientists who are researching aspects of epigenetics, including the role of genetic modification in altering the expression of genes in cancerous cells.

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Headline bioethics

June 3, 2011

The Headline Bioethics study guides are being hosted on the Virtual Genetics Education Centre at the University of Leicester

Headline bioethics is a new series of resources for teaching about bioethics. There will be two styles of Headline bioethics resources – study guides and commentaries. For both sets of material, each resource is focussed around a news story which raises interesting ethical question in the fields of biology and biomedicine. The selected stories must all be available as a video clip on the BBC news website.

Study guides include background information and structured worksheets which teachers can either use “of the shelf” or customise for their own purposes. Commentaries are authored by undergraduate students and offer reflections on some of the ethical issues raised by the news story.

The ethics of GM crops is one of the topics considered in Headline Bioethics

The first two study guides, on Genetically Modified crops and Preimplantation Genetic Diagnosis, are now available.  These Headline bioethics resources was authored by Sarah Curtis, a TULIP intern at the University of Leicester. If you have thoughts about these materials, or suggestions for future topics that you’d like to see covered in this way, then please let us know.