January 31, 2008
In 2000, the BBC launched Child of our time, an ambitious experiment to record the lives of twenty-five children over twenty years. The aim was to establish how our genes and the environment combine to make us who we are and shape our personality. Sir Robert Winston (IVF – A child against all odds) the fertility expert and TV personality presents the programmes as they follow a series of newborns from before birth through to adulthood.
|BBC ‘Child of our time’ Homepage
In this post we focus on two segments for the first series of Child of our time. These are: Series 1 The journey begins (00:22:00 – 00:28:40) and Series 1 – Birthdays (00:23:00 – 00:24:26). Both episodes are available online, see bottom of this post for details about how to access them.
This bioethical discussion, focuses on one set of parents, Neil and Gillian Roberts, who decide to be genetically tested for the Angiotensin I converting enzyme (ACE) gene. It has been suggested that certain variants of this gene help increase stamina and efficient use of oxygen, and thus have been linked to success in sporting activities The father, a keen athlete and sportsman, suggests that both he and the future mother be tested for this variant to establish whether their new born might subsequently have a chance of inheriting it. The result (which appears in the ‘Birthdays’ episode) is negative and neither parent has this particular variant. Read the rest of this entry »
January 23, 2008
I have to say from the outset that I am not usually a Hollyoaks fan and, as this post will show, I’m way off the pace as far as who’s who. However, turning on slightly early for the Channel 4 news on Tuesday 22nd January 2008 I happened to catch the end of that day’s episode of the Chester-based soap opera (TRILT code 007CA973) and was intrigued. The storyline involved Charlie, a baby recently diagnosed with Acute Myeloid Leukaemia (AML) and in need of a bone marrow transplant. The first clip I caught was the doctor informing Charlie’s ‘dad’ Jake Dean that a blood test revealed he was not a suitable donor for the baby – on the grounds that he was not, in fact, the boy’s biological father.
Frankie, Nancy and Jake
Recognising the potential benefit of this clip for teaching about transplantation and/or genetic testing, I decided I ought to check my facts. This, it turned out, is more complicated than I had anticipated. So (deep breath) the woman standing anxiously by the baby’s bedside is not Charlie’s mum, she is Nancy, Charlie’s aunt (no pun intended). Charlie’s mum Becca is dead, stabbed in prison by her cellmate. She was in prison having been found guilty of engaging in a sexual relationship with Justin, who was underage at the time. Despite the relationship being consensual, Justin made false claims of coercion based on his anger at being dumped by Becca. Justin is now with Katy Fox, Jake and Nancy are in a relationship of their own (keep up!). Knowing about Becca’s infidelity with Justin, Jake had ordered a paternity test in January 2007, but decided not to open it, choosing instead to remain in ignorance and bring up Charlie assuming that he was the biological father. This latest turn in the story shows that he is not. Read the rest of this entry »
January 21, 2008
Sharp-eyed users will have noticed the recent addition of a “Bioethics in the news” section in the side-bar.
This is a feed through from a del.icio.us tag (click on the title of the box to see the full listing). Because this is generated by members of the BioethicsBytes team rather than as an automated process, postings may occasionally refer to slightly older news stories if we’ve been looking back in the archives and found something worth tagging. Generally, however, the displayed links will relate to the latest news – we hope you find it useful.
January 11, 2008
The Biotech Revolution, the second episode of the BBC4 Visions of the Future series, continues to describe ways in which humanity is making a “historic transition from the age of scientific discovery to the age of scientific mastery”. Presenter Michio Kaku suggests that unlocking the basic code of life will allow us to “predetermine the destiny of life itself” and to manipulate it at the most fundamental level (Start-00:02:00).
The programme begins with Kaku having his “medical future rather than history” diagnosed via a series of genetic tests for complex diseases such as heart disease, diabetes and Alzheimer’s. He describes this as an “owner’s manual” which will enable him to have greater control of his health, and to allow others to perhaps prolong their life by decades (00:02:20-00:06:20 and 00:20:05-00:23: 20). As a scientist, he is eager to discover what secrets his genome may contain however, as a person, he says “wait a minute, this could be a Pandora’s Box… I’m looking at a side of me I have never seen before, a side that has potential medical problems lurking there”.
Some of the issues raised here mirror those found in the ITV1 broadcast The Killer in Me, which illustrated particularly well the anguish associated with having such tests and the way actions could be taken in light of the results. In this programme, in contrast, there is greater emphasis placed on the potential impact on relatives and wider society that may result from taking the tests. “We really want to respect your privacy and the privacy of your relatives” the physician emphasises to Kaku. Much of the future of this testing, if not the present, relies upon “the last great discovery of the 21st century, the Human Genome Project”. Kaku believes that this event holds such significance that we will look at the history of medicine in two eras, “before genome and after genome”. “Having unravelled the fundamental code of our biology the stage is set for us to manipulate it” he adds (00:06:25-00:09:20). Read the rest of this entry »
January 10, 2008
This episode of the BBC current affairs series Panorama follows the story of seven women with breast cancer who campaigned to receive the drug Herceptin. It is a classic example of the tensions arising from the rise in effective but expensive new medicines set against the constrained budget of the National Health Service. At the time of filming (Summer/Autumn 2005), treatment with Herceptin cost £30,000 per patient per year and was exclusively licensed for use against advanced-stage breast cancer. However in light of some promising and well-publicised clinical trials, and motivated by Prime Minister Tony Blair’s pledge that “Cancer patients in all parts of the country will get the right drugs at the right time, regardless of where they live” (00:02:50-00:03:10), seven women with early-stage breast cancer believed that this drug may well help save their lives. The programme follows their campaign as it snowballs from a local issue to achieve national support (00:11:45-00:13:50).
The central ethical question raised by this programme is, therefore, one of resource allocation. There is a cost-benefit analysis to be done for the treatment per se, but this also has to be seen in a broader context; a decision to fund one therapy means a decision elsewhere in the system that likely denies somebody the treatment that they want. How do you evaluate one course of treatment over another? How do you fairly distribute public resources between patients? Can you judge the value of one life against another? Read the rest of this entry »
January 9, 2008
In The Quantum Revolution, the final episode of BBC4’s Visions of the Future series, Michio Kaku explores the influence that our understanding of fundamental aspects of physics may have on our lives in the future. After outlining the origins and impact of quantum theory within physics during the 1960s (and on his own career path), Kaku describes how its implications have given us a new, and unprecedented power to manipulate matter at the atomic level.
|Michio Kaku presents Visions of the Future: The Quantum Revolution (BBC4, Nov 19 2007, 21:00)
The episode is effectively split into two halves. The first deals predominately with the the implications of quantum theory for energy production – specifically the possibility of truly sustainable, renewable energy sources – in the future; the second with the potential development of nanotechnology. The latter is the more bio-relevant and will be the focus of this commentary (approximately 00: 32:00 to 00:50:00).
Kaku describes nanotechnology as giving us the ability to “redesign the world by building with atoms” (00:32:05) and to control “the fundamentals of nature” (00:32:13). In introducing the viewer to nanotechnology, Kaku makes reference to what could be called ‘natural nanobots’ and states that “the goal of nanotechnology is to create living machines on the scale of cells like proteins, DNA or bacteria, and design them to perform equally complex tasks” (00:33:00). Specifically, he identifies three areas in which developments in nanotechnology may have a significant impact: bioremediation, biomedicine and the military. Read the rest of this entry »